What is HMB?
HMB is a derivative of the amino acid leucine and has been shown to protect against muscle loss associated with ageing or disease.1 It does this by slowing down muscle protein breakdown and supporting muscle protein synthesis.2
HMB is a derivative of the amino acid leucine and has been shown to protect against muscle loss associated with ageing or disease.1 It does this by slowing down muscle protein breakdown and supporting muscle protein synthesis.2
Helps preserve muscle mass3–5
Attenuates exercise-induced muscle damage6
Supports wound healing*7
*When supplemented in combination with glutamine and arginine.7
Studies suggest that the optimal daily dose of HMB is 3 g.4,8
HMB is naturally produced in small amounts by your body during the breakdown of leucine (an essential amino acid).9 HMB is found in small amounts in foods such as avocado, grapefruit, eggs and cauliflower.
From the age of 40 years, we lose around 8% of our muscle mass per decade.10 HMB supplementation has been shown to slow this process by slowing down muscle protein breakdown and supporting muscle protein synthesis.2
Food for Special Medical Purposes. Use only under medical supervision.
HMB: β-hydroxy-β-methylbutyrate.
References: 1. Stout JR, et al. Exp Gerontol. 2013 Nov;48(11):1303–10. 2. Argilés JM, et al. J Am Med Dir Assoc. 2016;17(9):789–96. 3. Lin Z, et al. Eur Geriatr Med. 2021;12(2):239–251. 4. Nissen SL, Abumrad NN. J Nutr Biochem. 1997;8:300–311. 5. Wilkinson DJ, et al. J Physiol. 2013; 591(11):2911–2923. 6. Holeček M. J Cachexia Sarcopenia Muscle. 2017;8(4):529–541. 7. Williams JZ, et al. Ann Surg. 2002;236(3):369–375. 8. Wilson GJ, et al. Nutr Metab (Lond). 2008;5:1. 9. Arazi H, et al. Antioxidants. 2018; 7(10):148. 10. Baier S, et al. JPEN J Parenter Enteral Nutr. 2009;33(1):71-82.
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