Fructo-oligosaccharides (FOS)

Fructo-oligosaccharides (FOS)

What are FOS?

FOS are a type of carbohydrate that are typically classified as soluble dietary fibre. FOS are considered prebiotics as they promote the growth and/or activity of the beneficial bacteria found in the colon.1

There are three types of FOS, each of which are structurally distinct, but have the same health benefits: inulin, oligofructose and sc-FOS (short chain FOS).1 You may find these terms on the ingredient lists of product labels.

Benefits of FOS

Helps growth of “good” bacteria in the colon1

Reduces some digestive issues1

Does not raise glucose levels2

Improves blood cholesterol levels1

FOS selectively stimulates the growth and activity of “good” bacteria in the gut, such as Bifidobacterium and Lactobacillus. As a byproduct of FOS digestion, “good” bacteria release beneficial substances in the host (e.g. short chain fatty acids), which support immune health and metabolism and have anti-inflammatory properties.1

It has been shown that FOS can help to reduce digestive issues, such as constipation.1 It may also help with managing intestinal inflammation.3

Unlike most carbohydrates (i.e. sugars and starches) FOS is not digested in the small intestine,1 and has a low glycaemic index.2 Studies have suggested that FOS may help reduce blood glucose levels, promote glucose absorption in peripheral tissues and indirectly improve insulin sensitivity.2

FOS consumption improves lipid metabolism.1 Cholesterol and triglycerides may contribute to hardening of the arteries or thickening of the artery walls (atherosclerosis).4 Atherosclerosis increases the risk of a number of heart diseases, including coronary artery disease, stroke and peripheral arterial disease.4 FOS reduces the levels of cholesterol and triglycerides in the bloodstream which may help to prevent heart disease.1

Recommended dietary intake (RDI) of FOS

While there is no RDI for FOS in Australia, it has been suggested that as little as 4 g of FOS daily is sufficient to boost the population of beneficial gut bacteria.*5,6

*Overconsumption of FOS (>20 g per day) and other dietary fibres has been associated with side effects, including gas and bloating.5

Sources of FOS

FOS naturally occurs in a variety of fruit and vegetables. Natural sources of FOS include blue agave, yacon root, garlic, onion, leek, chicory root, Jerusalem artichoke, asparagus and banana. They are also often found in paediatric and adult oral nutritional supplements to help maintain a healthy digestive system.

The importance of FOS

FOS selectively feeds only the good bacteria in the large intestine, helping to support gut health. A healthier gut not only aids in effective digestion, but is also linked to stronger immune system, heart health, potential prevention of some cancers and autoimmune diseases.7

Did you know?

FOS is commonly used as an alternative to sugar in foods.

Food for Special Medical Purposes. Use only under medical supervision.

FOS: fructo-oligosaccharides. GI: glycemic index. RDI: recommended daily intake. SCFA: short chain fatty acids. sc-FOS: short chain fructo-oligosaccharides.

References: 1. Sabater-Molina M, et al. J Physiol Biochem. 2009;65(3):315–328. 2. Caetano BF, et al. Nutrients. 2016;8(7):436. 3. Pituch-Zdanowska A, et al. Prz Gastroenterol. 2015;10(3):135–141. 4. Australian Institute of Health and Welfare (2023). Heart, stroke and vascular disease: Australian facts. Available at: https://www.aihw.gov.au/reports/heart-stroke-vascular-diseases/hsvd-facts/contents/risk-factors/abnormal-blood-lipids. Accessed: September 2023. 5. Tuohy KM, et al. Drug Discov Today. 2003;8(15):692–700. 6. Roberfroid, M.B, et al. J. Nutr. 1998;128:11–19. 7. Slavin J. Nutrients. 2013;5(4):1417–1435. 

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